Swissmedic authorised and GMP qualified production site

TRB’s Swiss industrial site, based in Vouvry, is mainly made up of two production units:

One is dedicated to the gangliosides* extraction and the second one to the manufacturing of hyaluronic acid based injectable products. The factory also owns a Research and Development unit which works closely with the production division. All TRB’s on-site innovative production methods and procedures are designed and implemented by the same R&D department. Thanks to our cutting-edge equipment, the company has achieved a high level of expertise in biotechnology, molecular biology, chemical extraction, synthesis and, finally, galenic. Our exclusive use of high quality ingredients ensures the excellence of TRB’s products, always with respect of the environment.

TRB’s hyaluronic acid based injectable products division and the GM1* production sites were developed and created by the plant’s technical department in accordance with applicable Good Manufacturing Practices (GMP) requirements. The technical department based at the factory boosts our flexibility and our integration capacity, whilst also strengthening TRB’s independence in development and engineering.  The isolation and purification process of gangliosides and monosialogangliosides were both entirely developed and scaled up at the Vouvry site. The ganglioside powder, used as a main raw material for GM1*, is obtained after several cleaning, extraction and purification steps, based on the TRB’s biotech know-how.

This raw material undergoes numerous industrial treatments, including concentration and dialysis, drawing on our biotech expertise for several steps in the process. After this processing, it then goes through an ion exchange resin based column (that purifies) in order to obtain a highly purified GM1*. In collaboration with the R&D department, the development of these techniques at an industrial scale has allowed TRB to broaden its purification and extraction expertise, in order to obtain high quality products. The production unit is equipped with distillation units allowing for the recycling of solvents, thus minimizing the environmental impact and optimising waste management.